diff --git a/setup.py b/setup.py
index 21e3841..337448b 100644
--- a/setup.py
+++ b/setup.py
@@ -46,9 +46,10 @@ setup(
     url='https://github.com/ethereum/vyper-debug',
     include_package_data=True,
     install_requires=[
-        "py-evm==0.2.0a26",
-        "eth-tester==0.1.0b28",
-        "vyper==0.1.0b3"
+        "py-evm==0.2.0a33",
+        "eth-tester==0.1.0b33",
+        "vyper==0.1.0b4",
+        "web3==4.8.1"
     ],
     setup_requires=['setuptools-markdown'],
     python_requires='>=3.6, <4',
diff --git a/vdb/debug_computation.py b/vdb/debug_computation.py
index a5e1be8..bca335d 100644
--- a/vdb/debug_computation.py
+++ b/vdb/debug_computation.py
@@ -1,11 +1,11 @@
-from evm.vm.forks.byzantium.computation import (
+from eth.vm.forks.byzantium.computation import (
     ByzantiumComputation,
 )
-from evm.exceptions import (
+from eth.exceptions import (
     Halt,
+    VMError
 )
 from vdb.vdb import VyperDebugCmd
-from evm.exceptions import VMError
 from vyper.exceptions import ParserException
 
 
@@ -97,7 +97,7 @@ class DebugComputation(ByzantiumComputation):
                     pos = cls.get_pos(pc_to_execute)
                     msg = e.args[0]
                     msg = "" if len(msg) == 0 else msg
-                    # import ipdb; ipdb.set_trace()
+
                     raise DebugVMError(
                         message=msg,
                         item=pos,
diff --git a/vdb/eth_tester_debug_backend.py b/vdb/eth_tester_debug_backend.py
index 85d34ea..a0bc6ee 100644
--- a/vdb/eth_tester_debug_backend.py
+++ b/vdb/eth_tester_debug_backend.py
@@ -1,17 +1,20 @@
-from evm.vm.forks.byzantium import ByzantiumVM
-from evm.vm.forks.byzantium.state import ByzantiumState
+from eth.chains.base import MiningChain
+from eth.db import get_db_backend
+from eth.vm.forks.byzantium import ByzantiumVM
+from eth.vm.forks.byzantium.state import ByzantiumState
 
 from vdb.debug_computation import DebugComputation
 
 from eth_tester.backends.pyevm.main import (
     get_default_genesis_params,
-    generate_genesis_state,
+    generate_genesis_state_for_keys,
     get_default_genesis_params,
     get_default_account_keys,
     PyEVMBackend
 )
 
 
+
 class DebugState(ByzantiumState):
     computation_class = DebugComputation
 
@@ -20,22 +23,21 @@ class DebugVM(ByzantiumVM):
     _state_class = DebugState  # type: Type[BaseState]
 
 
-def _setup_tester_chain():
-    from evm.chains.tester import MainnetTesterChain
-    from evm.db import get_db_backend
+def _setup_tester_chain(genesis_params, genesis_state, num_accounts):
 
     class DebugNoProofVM(DebugVM):
         """Byzantium VM rules, without validating any miner proof of work"""
 
+        @classmethod
         def validate_seal(self, header):
             pass
 
-    class MainnetTesterNoProofChain(MainnetTesterChain):
+    class MainnetTesterNoProofChain(MiningChain):
         vm_configuration = ((0, DebugNoProofVM), )
 
     genesis_params = get_default_genesis_params()
-    account_keys = get_default_account_keys()
-    genesis_state = generate_genesis_state(account_keys)
+    account_keys = get_default_account_keys(quantity=num_accounts)
+    genesis_state = generate_genesis_state_for_keys(account_keys)
 
     base_db = get_db_backend()
 
@@ -48,8 +50,9 @@ class PyEVMDebugBackend(PyEVMBackend):
     def __init__(self, ):
         super().__init__()
 
-    def reset_to_genesis(self):
-        self.account_keys, self.chain = _setup_tester_chain()
+    def reset_to_genesis(self, genesis_params=None, genesis_state=None, num_accounts=None):
+        self.account_keys, self.chain = _setup_tester_chain(genesis_params, genesis_state,
+                                                           num_accounts)
 
 
 def set_debug_info(source_code, source_map, stdin=None, stdout=None):
diff --git a/vdb/variables.py b/vdb/variables.py
index f1e759c..24c71f9 100644
--- a/vdb/variables.py
+++ b/vdb/variables.py
@@ -1,7 +1,7 @@
 from eth_hash.auto import keccak
 from eth_utils import to_hex
 from eth_abi import decode_single
-from evm.utils.numeric import (
+from eth.utils.numeric import (
     big_endian_to_int,
     int_to_big_endian,
 )
diff --git a/vdb/vdb.py b/vdb/vdb.py
index 3fb7055..b1733d1 100644
--- a/vdb/vdb.py
+++ b/vdb/vdb.py
@@ -6,9 +6,9 @@ from eth_utils import (
     to_int,
 )
 
-import evm
-from evm import constants
-from evm.vm.opcode import as_opcode
+import eth.vm
+from eth import constants
+from eth.vm.opcode import as_opcode
 from vyper.opcodes import opcodes as vyper_opcodes
 from vdb.variables import (
     parse_global,
@@ -215,7 +215,7 @@ class VyperDebugCmd(cmd.Cmd):
         return True
 
 
-original_opcodes = evm.vm.forks.byzantium.computation.ByzantiumComputation.opcodes
+original_opcodes = eth.vm.forks.byzantium.computation.ByzantiumComputation.opcodes
 
 
 def set_evm_opcode_debugger(source_code=None, source_map=None, stdin=None, stdout=None):
@@ -238,7 +238,7 @@ def set_evm_opcode_debugger(source_code=None, source_map=None, stdin=None, stdou
         gas_cost=0
     )
 
-    setattr(evm.vm.forks.byzantium.computation.ByzantiumComputation, 'opcodes', opcodes)
+    setattr(eth.vm.forks.byzantium.computation.ByzantiumComputation, 'opcodes', opcodes)
 
 
 def set_evm_opcode_pass():
@@ -252,4 +252,4 @@ def set_evm_opcode_pass():
         mnemonic="DEBUG",
         gas_cost=0
     )
-    setattr(evm.vm.forks.byzantium.computation.ByzantiumComputation, 'opcodes', opcodes)
+    setattr(eth.vm.forks.byzantium.computation.ByzantiumComputation, 'opcodes', opcodes)