diff --git a/Libraries/Utilities/__tests__/deepFreezeAndThrowOnMutationInDev-test.js b/Libraries/Utilities/__tests__/deepFreezeAndThrowOnMutationInDev-test.js
index 3ec7c7bab..4b5e11ea5 100644
--- a/Libraries/Utilities/__tests__/deepFreezeAndThrowOnMutationInDev-test.js
+++ b/Libraries/Utilities/__tests__/deepFreezeAndThrowOnMutationInDev-test.js
@@ -26,6 +26,13 @@ describe('deepFreezeAndThrowOnMutationInDev', function() {
     expect(() => deepFreezeAndThrowOnMutationInDev()).not.toThrow();
   });
 
+  it('should not throw on object without prototype', () => {
+    __DEV__ = true;
+    var o = Object.create(null);
+    o.key = 'Value';
+    expect(() => deepFreezeAndThrowOnMutationInDev(o)).not.toThrow();
+  });
+
   it('should throw on mutation in dev with strict', () => {
     'use strict';
     __DEV__ = true;
diff --git a/Libraries/Utilities/deepFreezeAndThrowOnMutationInDev.js b/Libraries/Utilities/deepFreezeAndThrowOnMutationInDev.js
index 71a29584a..2e2c4952e 100644
--- a/Libraries/Utilities/deepFreezeAndThrowOnMutationInDev.js
+++ b/Libraries/Utilities/deepFreezeAndThrowOnMutationInDev.js
@@ -39,12 +39,17 @@ function deepFreezeAndThrowOnMutationInDev<T: Object>(object: T): T {
     }
 
     const keys = Object.keys(object);
+    const hasOwnProperty = Object.prototype.hasOwnProperty;
 
     for (var i = 0; i < keys.length; i++) {
       var key = keys[i];
-      if (object.hasOwnProperty(key)) {
-        object.__defineGetter__(key, identity.bind(null, object[key]));
-        object.__defineSetter__(key, throwOnImmutableMutation.bind(null, key));
+      if (hasOwnProperty.call(object, key)) {
+        Object.defineProperty(object, key, {
+          get: identity.bind(null, object[key]),
+        });
+        Object.defineProperty(object, key, {
+          set: throwOnImmutableMutation.bind(null, key),
+        });
       }
     }
 
@@ -53,7 +58,7 @@ function deepFreezeAndThrowOnMutationInDev<T: Object>(object: T): T {
 
     for (var i = 0; i < keys.length; i++) {
       var key = keys[i];
-      if (object.hasOwnProperty(key)) {
+      if (hasOwnProperty.call(object, key)) {
         deepFreezeAndThrowOnMutationInDev(object[key]);
       }
     }