diff --git a/packages/metro-bundler/src/Resolver/polyfills/require.js b/packages/metro-bundler/src/Resolver/polyfills/require.js
index 3c1f0b24..f0e9e646 100644
--- a/packages/metro-bundler/src/Resolver/polyfills/require.js
+++ b/packages/metro-bundler/src/Resolver/polyfills/require.js
@@ -177,6 +177,7 @@ function loadModuleImplementation(moduleId, module) {
     if (!__DEV__) {
       // $FlowFixMe: This is only sound because we never access `factory` again
       module.factory = undefined;
+      module.dependencyMap = undefined;
     }
 
     if (__DEV__) {