diff --git a/.github/workflows/python-release.yml b/.github/workflows/python-release.yml
new file mode 100644
index 0000000..6180899
--- /dev/null
+++ b/.github/workflows/python-release.yml
@@ -0,0 +1,75 @@
+name: Python Package
+
+on:
+  release:
+    branches:
+      - main
+
+jobs:
+  build-wheels:
+    name: Build wheels for ${{ matrix.os }}
+    runs-on: ${{ matrix.os }}
+    strategy:
+      matrix:
+        os:
+          - ubuntu-latest
+          - windows-latest
+          - macos-13 # x86_64
+          - macos-14 # aarch64
+
+    steps:
+      - uses: actions/checkout@v4
+        with:
+          submodules: recursive
+
+      # On Linux, use QEMU to build multiple platforms.
+      - name: Setup QEMU
+        if: runner.os == 'Linux'
+        uses: docker/setup-qemu-action@v3
+        with:
+          platforms: all
+
+      # Need this for macos-14, which doesn't come with python for some reason.
+      - name: Setup Python
+        uses: actions/setup-python@v4
+        with:
+          python-version: '3.10'
+      
+      # Need this to get cl.exe on the path.
+      - name: Set up Visual Studio shell
+        if: runner.os == 'Windows'
+        uses: egor-tensin/vs-shell@v2
+
+      - name: Install cibuildwheel
+        run: python -m pip install cibuildwheel==2.16.5
+
+      - name: Build wheels
+        run: python -m cibuildwheel --output-dir wheelhouse bindings/python
+        env:
+
+          # We have QEMU setup and can build everything.
+          CIBW_ARCHS_LINUX: x86_64 i686 aarch64
+          # For some reason these don't use the same distro.
+          # musllinux uses apk & manylinux uses yum.
+          CIBW_BEFORE_BUILD_LINUX: |
+            if command -v apk > /dev/null; then
+              apk add --update clang && make -C src blst
+            elif command -v yum > /dev/null; then
+              yum install -y clang && make -C src blst
+            fi
+
+          # Building x86 (32-bit) package is difficult.
+          # We're missing the 32-bit Python library.
+          CIBW_ARCHS_WINDOWS: AMD64
+          # We need blst.lib (via MSVC) which our Makefile doesn't support.
+          CIBW_BEFORE_BUILD_WINDOWS: |
+            cd blst && build.bat && cp blst.lib ../lib && cp bindings/*.h ../inc
+
+          CIBW_BEFORE_BUILD_MACOS: |
+            make -C src blst
+
+      - name: Publish to PyPI
+        uses: pypa/gh-action-pypi-publish@release/v1
+        with:
+          password: ${{ secrets.PYPI_PASSWORD }}
+          packages-dir: bindings/python/wheelhouse
diff --git a/.github/workflows/python-tests.yml b/.github/workflows/python-tests.yml
index a444741..583d657 100644
--- a/.github/workflows/python-tests.yml
+++ b/.github/workflows/python-tests.yml
@@ -20,7 +20,6 @@ jobs:
       - name: Install dependencies
         run: |
           python -m pip install --upgrade pip
-          pip install py_ecc
           pip install PyYAML
       - name: Build BLST
         run: |
diff --git a/bindings/python/.gitignore b/bindings/python/.gitignore
index 567609b..6044606 100644
--- a/bindings/python/.gitignore
+++ b/bindings/python/.gitignore
@@ -1 +1,4 @@
 build/
+dist/
+ckzg.egg-info/
+src/
diff --git a/bindings/python/setup.py b/bindings/python/setup.py
index b072833..907da41 100644
--- a/bindings/python/setup.py
+++ b/bindings/python/setup.py
@@ -1,10 +1,12 @@
-from distutils.core import setup, Extension
+from setuptools import setup, Extension
+
 
 def main():
     setup(
         name="ckzg",
-        version="1.0.0",
-        description="Python interface for C-KZG-4844",
+        version="0.4.2",
+        author="Ethereum Foundation",
+        description="Python bindings for C-KZG-4844",
         ext_modules=[
             Extension(
                 "ckzg",
@@ -13,5 +15,6 @@ def main():
                 library_dirs=["../../lib"],
                 libraries=["blst"])])
 
+
 if __name__ == "__main__":
     main()