diff --git a/github/Repository.py b/github/Repository.py
index 5ae3d975..0f13f0ee 100644
--- a/github/Repository.py
+++ b/github/Repository.py
@@ -1252,7 +1252,7 @@ class Repository(github.GithubObject.CompletableGithubObject):
             url_parameters["ref"] = ref
         headers, data = self._requester.requestJsonAndCheck(
             "GET",
-            self.url + "/contents" + path,
+            self.url + "/contents" + urllib.quote(path),
             parameters=url_parameters
         )
         if isinstance(data, list):
@@ -1311,7 +1311,7 @@ class Repository(github.GithubObject.CompletableGithubObject):
 
         headers, data = self._requester.requestJsonAndCheck(
             "PUT",
-            self.url + "/contents" + path,
+            self.url + "/contents" + urllib.quote(path),
             input=put_parameters
         )
 
@@ -1370,7 +1370,7 @@ class Repository(github.GithubObject.CompletableGithubObject):
 
         headers, data = self._requester.requestJsonAndCheck(
             "PUT",
-            self.url + "/contents" + path,
+            self.url + "/contents" + urllib.quote(path),
             input=put_parameters
         )
 
@@ -1405,7 +1405,7 @@ class Repository(github.GithubObject.CompletableGithubObject):
 
         headers, data = self._requester.requestJsonAndCheck(
             "DELETE",
-            self.url + "/contents" + path,
+            self.url + "/contents" + urllib.quote(path),
             input=url_parameters
         )
 
@@ -1426,7 +1426,7 @@ class Repository(github.GithubObject.CompletableGithubObject):
             url_parameters["ref"] = ref
         headers, data = self._requester.requestJsonAndCheck(
             "GET",
-            self.url + "/contents" + path,
+            self.url + "/contents" + urllib.quote(path),
             parameters=url_parameters
         )