import datetime import enum import json import marshmallow from marshmallow import INCLUDE, fields from marshmallow_enum import EnumField from sqlalchemy import func from crc import db, ma from crc.api.common import ApiErrorSchema from crc.models.file import FileModel, SimpleFileSchema, FileSchema from crc.models.protocol_builder import ProtocolBuilderStatus, ProtocolBuilderStudy from crc.models.workflow import WorkflowSpecCategoryModel, WorkflowState, WorkflowStatus, WorkflowSpecModel, \ WorkflowModel from crc.services.user_service import UserService class StudyStatus(enum.Enum): in_progress = 'in_progress' hold = 'hold' open_for_enrollment = 'open_for_enrollment' abandoned = 'abandoned' class IrbStatus(enum.Enum): incomplete_in_protocol_builder = 'incomplete in protocol builder' completed_in_protocol_builder = 'completed in protocol builder' hsr_assigned = 'hsr number assigned' class StudyEventType(enum.Enum): user = 'user' automatic = 'automatic' class StudyModel(db.Model): __tablename__ = 'study' id = db.Column(db.Integer, primary_key=True) title = db.Column(db.String) last_updated = db.Column(db.DateTime(timezone=True), default=func.now()) status = db.Column(db.Enum(StudyStatus)) irb_status = db.Column(db.Enum(IrbStatus)) primary_investigator_id = db.Column(db.String, nullable=True) sponsor = db.Column(db.String, nullable=True) hsr_number = db.Column(db.String, nullable=True) ind_number = db.Column(db.String, nullable=True) user_uid = db.Column(db.String, db.ForeignKey('user.uid'), nullable=False) investigator_uids = db.Column(db.ARRAY(db.String), nullable=True) requirements = db.Column(db.ARRAY(db.Integer), nullable=True) on_hold = db.Column(db.Boolean, default=False) enrollment_date = db.Column(db.DateTime(timezone=True), nullable=True) # events = db.relationship("TaskEventModel") events_history = db.relationship("StudyEvent", cascade="all, delete, delete-orphan") def update_from_protocol_builder(self, pbs: ProtocolBuilderStudy): self.hsr_number = pbs.HSRNUMBER self.title = pbs.TITLE self.user_uid = pbs.NETBADGEID self.last_updated = pbs.DATE_MODIFIED self.irb_status = IrbStatus.incomplete_in_protocol_builder class StudyEvent(db.Model): __tablename__ = 'study_event' id = db.Column(db.Integer, primary_key=True) study_id = db.Column(db.Integer, db.ForeignKey(StudyModel.id), nullable=False) study = db.relationship(StudyModel, back_populates='events_history') create_date = db.Column(db.DateTime(timezone=True), default=func.now()) status = db.Column(db.Enum(StudyStatus)) comment = db.Column(db.String, default='') event_type = db.Column(db.Enum(StudyEventType)) user_uid = db.Column(db.String, db.ForeignKey('user.uid'), nullable=True) class WorkflowMetadata(object): def __init__(self, id, name = None, display_name = None, description = None, spec_version = None, category_id = None, category_display_name = None, state: WorkflowState = None, status: WorkflowStatus = None, total_tasks = None, completed_tasks = None, display_order = None): self.id = id self.name = name self.display_name = display_name self.description = description self.spec_version = spec_version self.category_id = category_id self.category_display_name = category_display_name self.state = state self.status = status self.total_tasks = total_tasks self.completed_tasks = completed_tasks self.display_order = display_order @classmethod def from_workflow(cls, workflow: WorkflowModel): instance = cls( id=workflow.id, name=workflow.workflow_spec.name, display_name=workflow.workflow_spec.display_name, description=workflow.workflow_spec.description, spec_version=workflow.spec_version(), category_id=workflow.workflow_spec.category_id, category_display_name=workflow.workflow_spec.category.display_name, state=WorkflowState.optional, status=workflow.status, total_tasks=workflow.total_tasks, completed_tasks=workflow.completed_tasks, display_order=workflow.workflow_spec.display_order ) return instance class WorkflowMetadataSchema(ma.Schema): state = EnumField(WorkflowState) status = EnumField(WorkflowStatus) class Meta: model = WorkflowMetadata additional = ["id", "name", "display_name", "description", "total_tasks", "completed_tasks", "display_order", "category_id", "category_display_name"] unknown = INCLUDE class Category(object): def __init__(self, model: WorkflowSpecCategoryModel): self.id = model.id self.name = model.name self.display_name = model.display_name self.display_order = model.display_order class CategorySchema(ma.Schema): workflows = fields.List(fields.Nested(WorkflowMetadataSchema), dump_only=True) class Meta: model = Category additional = ["id", "name", "display_name", "display_order"] unknown = INCLUDE class Study(object): def __init__(self, title, last_updated, primary_investigator_id, user_uid, id=None, status=None, irb_status=None, comment="", sponsor="", hsr_number="", ind_number="", categories=[], files=[], approvals=[], enrollment_date=None, events_history=[], **argsv): self.id = id self.user_uid = user_uid self.title = title self.last_updated = last_updated self.status = status self.irb_status = irb_status self.comment = comment self.primary_investigator_id = primary_investigator_id self.sponsor = sponsor self.hsr_number = hsr_number self.ind_number = ind_number self.categories = categories self.approvals = approvals self.warnings = [] self.files = files self.enrollment_date = enrollment_date self.events_history = events_history @classmethod def from_model(cls, study_model: StudyModel): id = study_model.id # Just read some value, in case the dict expired, otherwise dict may be empty. args = dict((k, v) for k, v in study_model.__dict__.items() if not k.startswith('_')) args['events_history'] = study_model.events_history # For some reason this attribute is not picked up instance = cls(**args) return instance def model_args(self): """Arguments that can be passed into the Study Model to update it.""" self_dict = self.__dict__.copy() del self_dict["categories"] del self_dict["warnings"] return self_dict class StudyForUpdateSchema(ma.Schema): id = fields.Integer(required=False, allow_none=True) status = EnumField(StudyStatus, by_value=True) hsr_number = fields.String(allow_none=True) sponsor = fields.String(allow_none=True) ind_number = fields.String(allow_none=True) enrollment_date = fields.DateTime(allow_none=True) comment = fields.String(allow_none=True) class Meta: model = Study unknown = INCLUDE @marshmallow.post_load def make_study(self, data, **kwargs): """Can load the basic study data for updates to the database, but categories are write only""" return Study(**data) class StudyEventSchema(ma.Schema): id = fields.Integer(required=False) create_date = fields.DateTime() status = EnumField(StudyStatus, by_value=True) comment = fields.String(allow_none=True) event_type = EnumField(StudyEvent, by_value=True) class StudySchema(ma.Schema): id = fields.Integer(required=False, allow_none=True) categories = fields.List(fields.Nested(CategorySchema), dump_only=True) warnings = fields.List(fields.Nested(ApiErrorSchema), dump_only=True) protocol_builder_status = EnumField(StudyStatus, by_value=True) status = EnumField(StudyStatus, by_value=True) hsr_number = fields.String(allow_none=True) sponsor = fields.String(allow_none=True) ind_number = fields.String(allow_none=True) files = fields.List(fields.Nested(FileSchema), dump_only=True) approvals = fields.List(fields.Nested('ApprovalSchema'), dump_only=True) enrollment_date = fields.Date(allow_none=True) events_history = fields.List(fields.Nested('StudyEventSchema'), dump_only=True) class Meta: model = Study additional = ["id", "title", "last_updated", "primary_investigator_id", "user_uid", "sponsor", "ind_number", "approvals", "files", "enrollment_date", "events_history"] unknown = INCLUDE @marshmallow.post_load def make_study(self, data, **kwargs): """Can load the basic study data for updates to the database, but categories are write only""" return Study(**data)